# Research Explore published research, case studies, and presentations from the Enable Medicine team. .svg) ## Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy ### Publication: June 29, 2024 #### Content Type: Patient response #### Technology Used: Single-cell, Spatial multi-omics [READ NOW](https://www.cell.com/cell-reports/fulltext/S2211-1247(24)00720-4#%20) ## A single-cell atlas of IL-23 inhibition in cutaneous psoriasis distinguishes clinical response ### Publication: January 26, 2024 #### Content Type: Patient response #### Technology Used: Single-cell transcriptomics [READ NOW](https://www.science.org/doi/10.1126/sciimmunol.adi2848) ## A machine learning toolkit for automated processing of multiplexed immunofluorescence images ### Publication: November 1, 2023 #### Content Type: Poster #### Technology Used: Image analysis, Tissue detection, Machine learning [READ NOW](/content/research/a-machine-learning-toolkit-for-automated-processing-of-multiplexed-immunofluorescence-images/index.html) ## From images to insights - Deep spatial profiling reveals disease and treatment biomarkers ### Publication: November 1, 2023 #### Content Type: Poster #### Technology Used: Spatial cellular profiling, Spatial proteomics [READ NOW](/content/research/from-images-to-insights---deep-spatial-profiling-reveals-disease-and-treatment-biomarkers/index.html) ## Integrative Spatial Multi-Omics Analysis of Nsclc Tumor Microenvironment Identifies Key Features Associated With Response to Immune Checkpoint Inhibitor Therapy ### Publication: November 1, 2023 #### Content Type: Poster #### Technology Used: Spatial-omics, Non-small cell lung cancer (NSCLC) [READ NOW](/content/research/integrative-spatial-multi-omics-analysis-of-nsclc-tumor-microenvironment-identifies-key-features-associated-with-response-to-immune-checkpoint-inhibitor-therapy/index.html) ## An end-to-end Visium spatial transcriptomics computational pipeline for generating low-code interactive reports of spatial insights ### Publication: November 1, 2023 #### Content Type: Poster #### Technology Used: Spatial transcriptomics [READ NOW](/content/research/an-end-to-end-visium-spatial-transcriptomics-computational-pipeline-for-generating-low-code-interactive-reports-of-spatial-insights/index.html) ## PEPSI: Polarity measurements from spatial proteomics imaging suggest immune cell engagement ### Publication: November 1, 2023 #### Content Type: Poster #### Technology Used: Cell phenotyping, Spatial proteomics [READ NOW](/content/research/pepsi-polarity-measurements-from-spatial-proteomics-imaging-suggest-immune-cell-engagement/index.html) ## Characterizing Tissue Structures from Spatial Omics with Spatial Cellular Graph Partition ### Publication: November 1, 2023 #### Content Type: Poster #### Technology Used: Tissue structure segmentation, Spatial-omics [READ NOW](/content/research/characterizing-tissue-structures-from-spatial-omics-with-spatial-cellular-graph-partition/index.html) ## emObject: An open-source domain-specific data abstraction for spatial omics ### Publication: November 1, 2023 #### Content Type: Poster #### Technology Used: Data abstraction, Spatial-omics [READ NOW](/content/research/emobject-an-open-source-domain-specific-data-abstraction-for-spatial-omics/index.html)